您有
玫瑰痤疮
的困扰吗
当脸上出现红斑、丘疹时,不少人以为是生暗疮,却忽略了患玫瑰痤疮的可能性。玫瑰痤疮和暗疮因症状相似而经常被混为一谈,但两者的治疗方式不同,不适当处理有可能令病情恶化。
什麽是玫瑰痤瘡?
玫瑰痤瘡(英文為Rosacea)是常見的慢性皮膚病,其徵狀包括面部微絲血管擴張,出現紅斑、丘疹或膿皰,嚴重的會有「酒渣鼻」和皮膚纖維化,甚至影響眼睛,出現眼睛乾澀、視力模糊、眼瞼紅腫等。
儘管目前還沒有完全根治玫瑰痤瘡的方法,但我們可以通過藥物治療和改變生活方式來控制。2 而常用的處方外用藥物有溴莫尼定凝膠(Brimonidine)和伊維菌素藥膏(Ivermectin)等等。1
溴莫尼定凝膠可於早上使用,能夠有效收縮皮膚血管,從而減少面部發紅。研究顯示,溴莫尼定凝膠約30 分鐘便能紓緩泛紅症狀,藥效長達12 小時,避免因於日間工作或外出社交時面紅紅的尷尬情況。3
而伊維菌素藥膏是較新一代治療丘疹膿皰型玫瑰痤瘡的藥物。它具有消炎和抗毛囊蟎蟲的效用,有助減少由玫瑰痤瘡引起的丘疹膿瘡。患者只需每天搽一次藥膏,而持續使用可減少80%的發炎丘疹膿皰,療效較傳統的甲硝唑藥膏略為優勝。4
要留意的是,一些玫瑰痤瘡的病徵與暗瘡、濕疹或牛皮癬相似5,不少患者會因錯誤地自我診斷而延誤就醫,甚至因胡亂塗藥而加劇病情。
约一半患者有家族遗传
女性的发病率比男性高
发病高峰期为夏季
常发于30-50岁人士
參考資料:
- 1. Solomon, C. G. (2017). Esther J. van Zuuren, MD. N Engl J Med, 377, 1754-64.
- 2. Rosacea. NHS inform. (n.d.). Retrieved April 28, 2023, from https://www.nhsinform.scot/illnesses-and-conditions/skin-hair-and-nails/rosacea#about-rosacea
- 3. Fowler Jr, J., Jackson, M., Moore, A., Jarratt, M., Jones, T., Meadows, K., ... & Leoni, M. (2013). Efficacy and safety of once-daily topical brimonidine tartrate gel 0.5% for the treatment of moderate to severe facial erythema of rosacea: results of two randomized, double-blind, and vehicle-controlled pivotal studies. Journal of drugs in dermatology: JDD, 12(6), 650-656.
- 4. Taieb, A., Ortonne, J. P., Ruzicka, T., Roszkiewicz, J., Berth‐Jones, J., Peirone, M. H., ... & Ivermectin Phase III Study Group. (2015). Superiority of ivermectin 1% cream over metronidazole 0· 75% cream in treating inflammatory lesions of rosacea: a randomized, investigator‐blinded trial. British Journal of Dermatology, 172(4), 1103-1110.
- 5. Red Skin & Rashes are not always the result of rosacea. National Rosacea Society. (n.d.). Retrieved April 28, 2023, from https://www.rosacea.org/blog/2016/june/red-skin-rashes-are-not-always-the-result-of-rosacea
- 6. Dall’Oglio, F., Fusto, C., & Micali, G. (2022). Intrafamilial transmission of rosacea spanning six generations: a retrospective observational study. The Journal of Clinical and Aesthetic Dermatology, 15(2), 35.[{{type}} Annotation]
- 7. Rosacea sufferers can enjoy summer without rise in flare-ups. Rosacea Sufferers Can Enjoy Summer Without Rise in Flare-ups | Rosacea.org. (n.d.). Retrieved April 28, 2023, from https://www.rosacea.org/rosacea-review/2001/summer/rosacea-sufferers-can-enjoy-summer-without-rise-in-flare-ups